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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 234482Generated: October 25, 2026

4-Ethoxyaniline → 3-(2-Chlorophenyl)-5-ethoxy-1,3-dihydroindol-2-one

https://huagongshe.com/reaction/234482

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-EthoxyanilineHCID 9076—
Reactant2-Chloromandelic acidHCID 97720—
Product3-(2-Chlorophenyl)-5-ethoxy-1,3-dihydroindol-2-oneHCID 19076627—

Reaction Steps

This compound is prepared according to the procedure described in step B of Preparation 66 from N-4-ethoxyphenyl-DL-2-chloromandelamide (120°-130° C.), itself obtained according to the procedure described in step A of Preparation 2 from 4-ethoxyaniline and DL-2-chloromandelic acid. This gives the expected product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05594023
Source datasetuspto-grants-1997_01
ORD IDord-40ba433ea85f47f3ab79f46534c84684
Source noteuspto-grants-1997_01