3-Amino-N-methylbenzamide → 5-fluoro-N4-(3-hydroxyphenyl)-N2-[3-[(N-methylamino)carbonyl]phenyl]-2,4-pyrimidinediamine
Reaction equation
[CH3:17][NH:18][C:19](=[O:20])[c:21]1[cH:22][c:23]([NH2:24])[cH:25][cH:26][cH:27]1.[Cl:1][c:2]1[n:3][cH:4][c:5]([F:16])[c:6]([NH:8][c:9]2[cH:10][c:11]([OH:15])[cH:12][cH:13][cH:14]2)[n:7]1>>[c:2]1([NH:24][c:23]2[cH:22][c:21]([C:19]([NH:18][CH3:17])=[O:20])[cH:27][cH:26][cH:25]2)[n:3][cH:4][c:5]([F:16])[c:6]([NH:8][c:9]2[cH:10][c:11]([OH:15])[cH:12][cH:13][cH:14]2)[n:7]1Participants
3
Sources & evidence
- ORD record
- ord-0420a1109a6541a0a5aeec118d2b7343
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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