Acetic Acid → 5-Methyl-N~2~-[4-(4-methylpiperazin-1-yl)phenyl]pyrimidine-2,4-diamine

HRID 2345577Notes

Reaction equation

HRID 2345577 reaction equation
[CH3:10][N:11]1[CH2:12][CH2:13][N:14]([c:17]2[cH:18][cH:19][c:20]([NH2:23])[cH:21][cH:22]2)[CH2:15][CH2:16]1.[CH3:24][C:25](=[O:26])[OH:27].[Cl:1][c:2]1[n:3][cH:4][c:5]([CH3:9])[c:6]([NH2:8])[n:7]1>>[c:2]1([NH:23][c:20]2[cH:19][cH:18][c:17]([N:14]3[CH2:13][CH2:12][N:11]([CH3:10])[CH2:16][CH2:15]3)[cH:22][cH:21]2)[n:3][cH:4][c:5]([CH3:9])[c:6]([NH2:8])[n:7]1

Participants

4

Reactant 3

HCID 176Acetic AcidHCID 7372534-(4-Methylpiperazin-1-yl)anilineHCID 43021752-Chloro-5-methylpyrimidin-4-amine

Product 1

HCID 569241695-Methyl-N~2~-[4-(4-methylpiperazin-1-yl)phenyl]pyrimidine-2,4-diamine

Sources & evidence

ORD record
ord-cac8296be8f34a66922afce57ed9758c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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