Benzoic acid, 4-(acetyloxy)- → p-Acetoxybenzoyl chloride

Participants

Reaction Conditions

Reaction Steps

In a 200 ml-reaction vessel, 21.4 g (1.18×10-1M) of p-acetoxybenzoic acid and 80 ml of dry benzene were placed. To the mixture, 25.0 g (1.20×10-1M) of phosphorus pentachloride was added in 10 minutes at room temperature, followed by stirring for 3 hours at 50° C. After cooling, the solvent of the reaction mixture was distilled off to provide oily p-acetoxybenzoyl chloride.

Provenance & Evidence