4-Bromo-3-fluorobenzotrifluoride → Methyl 5-[2-fluoro-4-(trifluoromethyl)phenyl]nicotinate

HRID 2345959Notes

Reaction equation

HRID 2345959 reaction equation
[Br:1][c:2]1[c:3]([F:12])[cH:4][c:5]([C:8]([F:9])([F:10])[F:11])[cH:6][cH:7]1.[CH3:13][C:14]1([CH3:15])[C:16]([CH3:17])([CH3:18])[O:19][B:20]([c:21]2[cH:22][n:23][cH:24][c:25]([C:26](=[O:27])[O:28][CH3:29])[cH:30]2)[O:31]1>>[c:2]1(-[c:21]2[cH:22][n:23][cH:24][c:25]([C:26](=[O:27])[O:28][CH3:29])[cH:30]2)[c:3]([F:12])[cH:4][c:5]([C:8]([F:9])([F:10])[F:11])[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 1424144-Bromo-3-fluorobenzotrifluorideHCID 177502573-(Methoxycarbonyl)pyridine-5-boronic acid, pinacol ester

Product 1

HCID 58116584Methyl 5-[2-fluoro-4-(trifluoromethyl)phenyl]nicotinate

Sources & evidence

ORD record
ord-db557e9f1e774eb48d851d945f491185
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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