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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 234615Generated: October 29, 2026

Aminoacetaldehyde dimethyl acetal → HCID 178495966, compound

https://huagongshe.com/reaction/234615

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAminoacetaldehyde dimethyl acetalHCID 89728—
ReactantEthyl 2-(thiophen-3-yl)ethanimidate--hydrogen chloride (1/1)HCID 23355011—
Solvent1,2-DimethoxyethaneHCID 8071—
ProductHCID 178495966HCID 178495966—

Reaction Conditions

Temperature15 °C

Reaction Steps

A mixture of O-ethyl 3-thiopheneethanimidate hydrochloride (0.14 mol) in 1,2-dimethoxyethane (150 ml) was stirred at 15° C. 2,2-dimethoxyethanamine (0.14 mol) was added portionwise and the mixture was stirred overnight. The mixture was evaporated, yielding N-(2,2-dimethoxyethyl)-3-thiopheneethanimidamide monohydrochloride (interm. 13).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05595988
Source datasetuspto-grants-1997_01
ORD IDord-97a9d938517046e1a774f2b9c91c7706
Source noteuspto-grants-1997_01