(RS)-N-(4-cyano-benzyl)-2-(2,6-difluoro-3-hydroxy-phenyl)-2-ethoxy-acetamide → (RS)-N-(4-Cyano-benzyl)-2-(2,6-difluoro-3-hydroxy-phenyl)-2-methoxy-acetamide

HRID 2346160Notes

Reaction equation

HRID 2346160 reaction equation
[C:16](#[N:17])[c:18]1[cH:19][cH:20][c:21]([CH2:22][NH:23][C:24]([CH:25]([O:26][CH2:27][CH3:28])[c:29]2[c:30]([F:37])[c:31]([OH:36])[cH:32][cH:33][c:34]2[F:35])=[O:38])[cH:39][cH:40]1.[F:1][c:2]1[c:3]([OH:4])[cH:5][cH:6][c:7]([F:8])[c:9]1[CH:10]([O:11][CH3:12])[C:13]([OH:14])=[O:15]>>[C:16](#[N:17])[c:18]1[cH:19][cH:20][c:21]([CH2:22][NH:23][C:24]([CH:25]([O:26][CH3:27])[c:29]2[c:30]([F:37])[c:31]([OH:36])[cH:32][cH:33][c:34]2[F:35])=[O:38])[cH:39][cH:40]1

Participants

3

Reactant 2

HCID 21905759(RS)-N-(4-cyano-benzyl)-2-(2,6-difluoro-3-hydroxy-phenyl)-2-ethoxy-acetamideHCID 69290134(RS)-(2,6-difluoro-3-hydroxy-phenyl)-methoxy-acetic acid

Product 1

HCID 21905078(RS)-N-(4-Cyano-benzyl)-2-(2,6-difluoro-3-hydroxy-phenyl)-2-methoxy-acetamide

Sources & evidence

ORD record
ord-d1be2567da154ea4bbcf1f7ae833a0bf
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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