Dimethyl Sulfoxide → 3,5-Dimethyl-1-(4-nitrophenyl)piperazine

HRID 2346168Notes

Reaction equation

HRID 2346168 reaction equation
[C:11](=[O:12])([O-:13])[O-:14].[CH3:17][CH:18]1[CH2:19][NH:20][CH2:21][CH:22]([CH3:24])[NH:23]1.[CH3:25][S:26]([CH3:27])=[O:28].[F:1][c:2]1[cH:3][cH:4][c:5]([N+:8](=[O:9])[O-:10])[cH:6][cH:7]1.[K+:15].[K+:16].[OH2:29]>>[c:2]1([N:20]2[CH2:19][CH:18]([CH3:17])[NH:23][CH:22]([CH3:24])[CH2:21]2)[cH:3][cH:4][c:5]([N+:8](=[O:9])[O-:10])[cH:6][cH:7]1

Participants

7

Reactant 6

HCID 679Dimethyl SulfoxideHCID 813Potassium Cation2×HCID 962WaterHCID 9590p-FluoronitrobenzeneHCID 19660Carbonate IonHCID 660562,6-Dimethylpiperazine

Product 1

HCID 28296203,5-Dimethyl-1-(4-nitrophenyl)piperazine

Sources & evidence

ORD record
ord-7a2f6572ce084975b9adcbcc499ce697
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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