8-(4-Fluorophenyl)-1,4-dioxaspiro[4.5]dec-7-ene → 8-(4-Fluorophenyl)-1,4-dioxaspiro[4.5]decane

HRID 234619Notes

Reaction equation

HRID 234619 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH2:17][CH2:16][C:11]3([O:15][CH2:14][CH2:13][O:12]3)[CH2:10][CH:9]=2)=[CH:4][CH:3]=1>C(O)C.[Pt]=O>[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]2[CH2:17][CH2:16][C:11]3([O:12][CH2:13][CH2:14][O:15]3)[CH2:10][CH2:9]2)=[CH:4][CH:3]=1

Participants

4

Reactant 1

HCID 152326828-(4-Fluorophenyl)-1,4-dioxaspiro[4.5]dec-7-ene

Product 1

HCID 128344048-(4-Fluorophenyl)-1,4-dioxaspiro[4.5]decaneYield 100%

Reagents, catalysts & solvents 2

HCID 82844Platinum oxide (PtO)CatalystHCID 702EthanolSolvent

Procedure

A mixture of 8-(4-fluorophenyl)-1,4-dioxaspiro[4,5]dec-7-ene (36.7 mmole) and platinum oxide (0.15 g) was hydrogenated in ethanol for 1.5 hr. The catalyst was removed by filtration and the ethanol removed in vacuo to give the product (100%, mp: 51°-53° C.). Calc'd for C14H17FO2 : C, 71.17%; H, 7.26%. Found: C, 71.16%; H, 7.35%.

Workup

  1. customThe catalyst was removed by filtration
  2. customthe ethanol removed in vacuo

Sources & evidence

ORD record
ord-d0f706f22ea24121903094427c94ad73
Source dataset
uspto-grants-1997_01
Patent number
US05595993

Reaction notes

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