tert-Butyl piperazine-1-carboxylate → HCID 178452338, compound

HRID 234626Notes

Reaction equation

HRID 234626 reaction equation
[O:1]1[C:5]2[CH:6]=[CH:7][C:8]([CH:10]3[CH2:15][CH2:14][C:13](=O)[CH2:12][CH2:11]3)=[CH:9][C:4]=2[O:3][CH2:2]1.[N:17]1([C:23]([O:25][C:26]([CH3:29])([CH3:28])[CH3:27])=[O:24])[CH2:22][CH2:21][NH:20][CH2:19][CH2:18]1>>[O:1]1[C:5]2[CH:6]=[CH:7][C:8]([C@H:10]3[CH2:15][CH2:14][C@H:13]([N:20]4[CH2:19][CH2:18][N:17]([C:23]([O:25][C:26]([CH3:29])([CH3:28])[CH3:27])=[O:24])[CH2:22][CH2:21]4)[CH2:12][CH2:11]3)=[CH:9][C:4]=2[O:3][CH2:2]1

Participants

3

Reactant 2

HCID 143452tert-Butyl piperazine-1-carboxylateHCID 10932904AGN-PC-0ND25R

Product 1

HCID 178452338HCID 178452338, compoundYield 88%

Procedure

4-(1,3-Benzodioxol-5-yl)cyclohexanone and 1,1-dimethylethyl 1-piperazine carboxylate were reacted as described in example 9 to give the product (88%, mp: 121°-122° C.). Calc'd for C22H32N2O4 : C, 68.01%; H, 8.31%; N, 7.22%. Found: C, 67.61%; H, 8.24%; N, 7.07%.

Sources & evidence

ORD record
ord-11b60a61075a41f7b51e0f02698308a4
Source dataset
uspto-grants-1997_01
Patent number
US05595993

Reaction notes

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