3-Methoxybenzyl chloride → HCID 178490266, compound

HRID 234631Notes

Reaction equation

HRID 234631 reaction equation
[O:1]1[C:5]2[CH:6]=[CH:7][C:8]([C@H:10]3[CH2:15][CH2:14][C@H:13]([N:16]4[CH2:21][CH2:20][NH:19][CH2:18][CH2:17]4)[CH2:12][CH2:11]3)=[CH:9][C:4]=2[O:3][CH2:2]1.[CH3:22][O:23][C:24]1[CH:25]=[C:26]([CH:29]=[CH:30][CH:31]=1)[CH2:27]Cl>>[O:1]1[C:5]2[CH:6]=[CH:7][C:8]([C@H:10]3[CH2:15][CH2:14][C@H:13]([N:16]4[CH2:21][CH2:20][N:19]([CH2:27][C:26]5[CH:29]=[CH:30][CH:31]=[C:24]([O:23][CH3:22])[CH:25]=5)[CH2:18][CH2:17]4)[CH2:12][CH2:11]3)=[CH:9][C:4]=2[O:3][CH2:2]1

Participants

3

Reactant 2

HCID 699943-Methoxybenzyl chlorideHCID 178420444HCID 178420444, compound

Product 1

HCID 178490266HCID 178490266, compound

Procedure

The title compound was prepared from trans 1-[4-(1,3-benzodioxol-5-yl)-1-cyclohexyl]piperazine and 3-methoxybenzyl chloride by the method described in example 15 to give the product (67%, mp: 93°-96° C.). Calc'd for C25H32N2O3 : C, 73.50%; H, 7.90%; N, 6.86%. Found: C, 73.23%; H, 7.92%; N, 6.99%.

Sources & evidence

ORD record
ord-09fe8d4bcde14320af76ad43ef7a733a
Source dataset
uspto-grants-1997_01
Patent number
US05595993

Reaction notes

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