Ammonia → Methyl 4-amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylate

HRID 2346365Notes

Reaction equation

HRID 2346365 reaction equation
[CH3:20][OH:21].[CH3:23][OH:24].[NH2:6][c:7]1[c:8]([Cl:19])[cH:9][c:10]([C:16](=[O:17])[OH:18])[c:11]2[c:12]1[CH2:13][CH2:14][O:15]2.[NH3:22].[S:1](=[O:2])(=[O:3])([OH:4])[OH:5]>>[NH2:6][c:7]1[c:8]([Cl:19])[cH:9][c:10]([C:16](=[O:17])[O:18][CH3:20])[c:11]2[c:12]1[CH2:13][CH2:14][O:15]2

Participants

5

Reactant 4

HCID 222AmmoniaHCID 887Methanol2×HCID 1118Sulfuric AcidHCID 106324014-Amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylic acid

Product 1

HCID 54393661Methyl 4-amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylate

Sources & evidence

ORD record
ord-083cb5ee7ef94f8fbdb5153c21e285a0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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