Acetic Acid → 5-[1-[tert-butyl(dimethyl)silyl]oxy-2-[[3-[3-[4-(2-methyl-1,3-thiazole-4-carbonyl)-1-oxa-4,9-diazaspiro[5.5]undecan-9-yl]propoxy]phenyl]methylamino]ethyl]-8-hydroxy-1H-quinolin-2-one
Reaction equation
[C:1]([O:2][BH-:3]([O:4][C:5](=[O:6])[CH3:7])[O:8][C:9](=[O:10])[CH3:11])(=[O:12])[CH3:13].[CH3:15][c:16]1[s:17][cH:18][c:19]([C:21](=[O:22])[N:23]2[CH2:24][CH2:25][O:26][C:27]3([CH2:28]2)[CH2:29][CH2:30][N:31]([CH2:34][CH2:35][CH2:36][O:37][c:38]2[cH:39][c:40]([CH:41]=[O:42])[cH:43][cH:44][cH:45]2)[CH2:32][CH2:33]3)[n:20]1.[CH3:69][C:70](=[O:71])[OH:72].[CH3:73][OH:74].[NH2:46][CH2:47][CH:48]([O:49][Si:50]([CH3:51])([CH3:52])[C:53]([CH3:54])([CH3:55])[CH3:56])[c:57]1[c:58]2[cH:59][cH:60][c:61](=[O:68])[nH:62][c:63]2[c:64]([OH:67])[cH:65][cH:66]1.[Na+:14]>>[CH3:15][c:16]1[s:17][cH:18][c:19]([C:21](=[O:22])[N:23]2[CH2:24][CH2:25][O:26][C:27]3([CH2:28]2)[CH2:29][CH2:30][N:31]([CH2:34][CH2:35][CH2:36][O:37][c:38]2[cH:39][c:40]([CH2:41][NH:46][CH2:47][CH:48]([O:49][Si:50]([CH3:51])([CH3:52])[C:53]([CH3:54])([CH3:55])[CH3:56])[c:57]4[c:58]5[cH:59][cH:60][c:61](=[O:68])[nH:62][c:63]5[c:64]([OH:67])[cH:65][cH:66]4)[cH:43][cH:44][cH:45]2)[CH2:32][CH2:33]3)[n:20]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-21d0e23cb74141fa8a1407ed65e46a23
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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