2-(Bromomethyl)-3-chloro-1,4-difluorobenzene → 6-(3-Aminopiperidin-1-yl)-1-[(2-chloro-3,6-difluorophenyl)methyl]-3-methylpyrimidine-2,4-dione
Reaction equation
[Cl:26][c:27]1[c:28]([CH2:29][Br:30])[c:31]([F:36])[cH:32][cH:33][c:34]1[F:35].[NH2:1][CH:2]1[CH2:3][N:4]([c:8]2[cH:9][c:10](=[O:25])[n:11]([CH3:24])[c:12](=[O:23])[n:13]2[CH2:14][c:15]2[cH:16][c:17]([F:18])[cH:19][cH:20][c:21]2[Br:22])[CH2:5][CH2:6][CH2:7]1>>[NH2:1][CH:2]1[CH2:3][N:4]([c:8]2[cH:9][c:10](=[O:25])[n:11]([CH3:24])[c:12](=[O:23])[n:13]2[CH2:29][c:28]2[c:27]([Cl:26])[c:34]([F:35])[cH:33][cH:32][c:31]2[F:36])[CH2:5][CH2:6][CH2:7]1Participants
3
Sources & evidence
- ORD record
- ord-9ca1ed934e6f4a8f93ef38e9292b2c12
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
Loading…