Acetone → HCID 23355216, compound

HRID 234693Notes

Reaction equation

HRID 234693 reaction equation
Cl.Cl[CH2:3][CH2:4][NH:5][C:6]1[C:15]2[C:10](=[CH:11][C:12]([Cl:16])=[CH:13][CH:14]=2)[N:9]=[CH:8][CH:7]=1.[CH3:17][C:18]([CH3:20])=O>>[Cl:16][C:12]1[CH:11]=[C:10]2[C:15]([C:6]([NH:5][CH2:4][CH2:3][N:5]3[CH:6]([CH3:15])[CH2:7][CH2:17][CH:18]3[CH3:20])=[CH:7][CH:8]=[N:9]2)=[CH:14][CH:13]=1

Participants

3

Reactant 2

HCID 180AcetoneHCID 23355222HCID 23355222, compound

Product 1

HCID 23355216HCID 23355216, compound

Procedure

0.35 g (isomer mixture cis:trans=15:1) from 1.3 g of N-(2-chloroethyl)-7-chloro-4-quinolinamine hydrochloride; yellowish crystals from acetone, m.p.: 127°-130° C.

Sources & evidence

ORD record
ord-e138acf39a264b69b4edca51be7ff538
Source dataset
uspto-grants-1997_01
Patent number
US05596002

Reaction notes

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