Dichloromethane → 4-Chloro-3-[2-(2-chloro-pyridin-4-yl)-3,3,3-trifluoro-2-hydroxy-1-methyl-propyl]-phenol

HRID 2347050Notes

Reaction equation

HRID 2347050 reaction equation
[B:25]([Br:26])([Br:27])[Br:28].[Cl:1][c:2]1[c:3]([CH:10]([C:11]([C:12]([F:13])([F:14])[F:15])([OH:16])[c:17]2[cH:18][c:19]([Cl:23])[n:20][cH:21][cH:22]2)[CH3:24])[cH:4][c:5]([O:8][CH3:9])[cH:6][cH:7]1.[Cl:29][CH2:30][Cl:31]>>[Cl:1][c:2]1[c:3]([CH:10]([C:11]([C:12]([F:13])([F:14])[F:15])([OH:16])[c:17]2[cH:18][c:19]([Cl:23])[n:20][cH:21][cH:22]2)[CH3:24])[cH:4][c:5]([OH:8])[cH:6][cH:7]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 25134Boron tribromideHCID 252544523-(2-Chloro-5-methoxy-phenyl)-2-(2-chloro-pyridin-4-yl)-1,1,1-trifluoro-butan-2-ol

Product 1

HCID 252546034-Chloro-3-[2-(2-chloro-pyridin-4-yl)-3,3,3-trifluoro-2-hydroxy-1-methyl-propyl]-phenol

Sources & evidence

ORD record
ord-81662f94bba44275b9f537952f43a0f1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

Loading…