Acetic Anhydride → 2(3H)-Thiazolethione, 3-(acetyloxy)-4-methyl-

Participants

Reaction Steps

0.74 parts of 3-hydroxy-4-methylthiazol-2(3H)-thione, 0.84 parts of sodium bicarbonate and 30 parts of water were stirred at 0°-5° C. while 0.52 parts of acetic anhydride were added dropwise and the reaction mixture was stirred at 0°-5° C. for a further hour. A precipitate was formed which was separated by filtration and recrystallised from aqueous methanol. 0.33 parts of 3-acetoxy-4-methylthiazol-2(3H)-thione, of melting point 100°-101° C., was obtained.

Provenance & Evidence