4-Benzyloxy-2(1H)-pyridone → 2-(4-(Benzyloxy)-2-oxopyridin-1(2H)-yl)-N-(3,4-difluorobenzyl)-4-methylthiazole-5-carboxamide
Reaction equation
[Br:16][c:17]1[s:18][c:19]([C:23](=[O:24])[NH:25][CH2:26][c:27]2[cH:28][c:29]([F:34])[c:30]([F:33])[cH:31][cH:32]2)[c:20]([CH3:22])[n:21]1.[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][c:11](=[O:15])[nH:12][cH:13][cH:14]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][c:11](=[O:15])[n:12](-[c:17]2[s:18][c:19]([C:23](=[O:24])[NH:25][CH2:26][c:27]3[cH:28][c:29]([F:34])[c:30]([F:33])[cH:31][cH:32]3)[c:20]([CH3:22])[n:21]2)[cH:13][cH:14]1Participants
3
Sources & evidence
- ORD record
- ord-7137bdcdfe2b4011a723be6d9394af71
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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