Methanol → (1'-Benzylspiro[benzo[b]pyrrolo[1,2-d][1,4]oxazine-4,4'-piperidine]-1-yl)methanol

HRID 2348027Notes

Reaction equation

HRID 2348027 reaction equation
[BH4-:28].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][C:11]2([c:12]3[n:13]([c:21]([CH:24]=[O:25])[cH:22][cH:23]3)-[c:14]3[c:15]([cH:17][cH:18][cH:19][cH:20]3)[O:16]2)[CH2:26][CH2:27]1.[CH3:30][OH:31].[Na+:29]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][C:11]2([c:12]3[n:13]([c:21]([CH2:24][OH:25])[cH:22][cH:23]3)-[c:14]3[c:15]([cH:17][cH:18][cH:19][cH:20]3)[O:16]2)[CH2:26][CH2:27]1

Participants

5

Reactant 4

HCID 887MethanolHCID 923Sodium ionHCID 28123BorohydrideHCID 585509691'-Benzylspiro[benzo[b]pyrrolo[1,2-d][1,4]oxazine-4,4'-piperidine]-1-carbaldehyde

Product 1

HCID 58550905(1'-Benzylspiro[benzo[b]pyrrolo[1,2-d][1,4]oxazine-4,4'-piperidine]-1-yl)methanol

Sources & evidence

ORD record
ord-666e87b4f0ec4da38db05fd930e6a4d3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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