Ethanol → 4-(3-Bromopyridin-4-yloxy)-2,5-difluorobenzenamine

HRID 2348079Notes

Reaction equation

HRID 2348079 reaction equation
[Br:1][c:2]1[cH:3][n:4][cH:5][cH:6][c:7]1[O:8][c:9]1[c:10]([F:19])[cH:11][c:12]([N+:16]([O-:17])=[O:18])[c:13]([F:15])[cH:14]1.[CH3:25][CH2:26][OH:27].[OH2:20].[OH2:21].[Sn:22]([Cl:23])[Cl:24]>>[Br:1][c:2]1[cH:3][n:4][cH:5][cH:6][c:7]1[O:8][c:9]1[c:10]([F:19])[cH:11][c:12]([NH2:16])[c:13]([F:15])[cH:14]1

Participants

5

Reactant 4

HCID 702EthanolHCID 962Water2×HCID 24479Stannous ChlorideHCID 673986343-Bromo-4-(2,5-difluoro-4-nitrophenoxy)pyridine

Product 1

HCID 673992554-(3-Bromopyridin-4-yloxy)-2,5-difluorobenzenamine

Sources & evidence

ORD record
ord-c492fd1ddcbc47a887bc3198239fc252
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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