Methanol → 2-tert-butyl-3-(2,2-dimethoxy-ethyl)-1H-indol-6-ylamine

HRID 2348183Notes

Reaction equation

HRID 2348183 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[nH:6][c:7]2[cH:8][c:9]([N+:20]([O-:21])=[O:22])[cH:10][cH:11][c:12]2[c:13]1[CH2:14][CH:15]([O:16][CH3:17])[O:18][CH3:19].[CH3:23][OH:24].[OH-:25].[OH-:27].[Pd+2:26]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[nH:6][c:7]2[cH:8][c:9]([NH2:20])[cH:10][cH:11][c:12]2[c:13]1[CH2:14][CH:15]([O:16][CH3:17])[O:18][CH3:19]

Participants

5

Reactant 4

HCID 887MethanolHCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 578992342-tert-butyl-3-(2,2-dimethoxy-ethyl)-6-nitro-1H-indole

Product 1

HCID 578993052-tert-butyl-3-(2,2-dimethoxy-ethyl)-1H-indol-6-ylamine

Sources & evidence

ORD record
ord-087e0bdfcebb4519bbed5c2cc0959f39
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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