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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2348328Generated: November 1, 2026

Acetic Acid → 3-Benzyloxymethyl-1-(2,6-dimethylphenyl)-5-oxo-pyrrolidine-3-carboxylic acid (3,5-bis-trifluoromethylphenyl)-amide

https://huagongshe.com/reaction/2348328

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantTetrahydrofuranHCID 8028—
ReactantBenzenamine, 3,5-bis(trifluoromethyl)-HCID 9480—
Reactant3-Benzyloxymethyl-1-(2,6-dimethylphenyl)-5-oxo-pyrrolidine-3-carboxylic acid methyl esterHCID 58218768—
ReactantButyllithiumHCID 178418339—
Product3-Benzyloxymethyl-1-(2,6-dimethylphenyl)-5-oxo-pyrrolidine-3-carboxylic acid (3,5-bis-trifluoromethylphenyl)-amideHCID 51034681—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (10/10)
ORD IDord-b6af21f05242402e95d190cdbbcc2bd3
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (10/10)