Acetonitrile → Ethyl 4-((4-methoxybenzyl)oxy)-6-(trifluoromethyl)quinoline-2-carboxylate

HRID 2348377Notes

Reaction equation

HRID 2348377 reaction equation
[C:31](=[O:32])([O-:33])[O-:34].[CH3:37][C:38]#[N:39].[Cl:21][CH2:22][c:23]1[cH:24][cH:25][c:26]([O:29][CH3:30])[cH:27][cH:28]1.[Cs+:35].[Cs+:36].[OH:1][c:2]1[cH:3][c:4]([C:16](=[O:17])[O:18][CH2:19][CH3:20])[n:5][c:6]2[cH:7][cH:8][c:9]([C:12]([F:13])([F:14])[F:15])[cH:10][c:11]12>>[O:1]([c:2]1[cH:3][c:4]([C:16](=[O:17])[O:18][CH2:19][CH3:20])[n:5][c:6]2[cH:7][cH:8][c:9]([C:12]([F:13])([F:14])[F:15])[cH:10][c:11]12)[CH2:22][c:23]1[cH:24][cH:25][c:26]([O:29][CH3:30])[cH:27][cH:28]1

Participants

6

Reactant 5

HCID 6342AcetonitrileHCID 19660Carbonate IonHCID 699934-Methyloxybenzyl chlorideHCID 104967Cesium cation2×HCID 178469289HCID 178469289, compound

Product 1

HCID 58562636Ethyl 4-((4-methoxybenzyl)oxy)-6-(trifluoromethyl)quinoline-2-carboxylate

Sources & evidence

ORD record
ord-2ac8aa12cc6945bd977cdc4333e1fcbf
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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