HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2348425Generated: October 31, 2026
1,2-Dichloroethane → 1-[[4-Thiophen-2-ylsulfonyl-1-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]piperazin-2-yl]methylamino]cyclobutane-1-carbonitrile
https://huagongshe.com/reaction/2348425
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1,2-Dichloroethane | HCID 11 | — |
| Reactant | Cyclobutanone | HCID 14496 | — |
| Reactant | Trimethylsilyl cyanide | HCID 82115 | — |
| Reactant | 2-[4-[2-(Aminomethyl)-4-thiophen-2-ylsulfonylpiperazin-1-yl]phenyl]-1,1,1-trifluoropropan-2-ol | HCID 77148386 | — |
| Product | 1-[[4-Thiophen-2-ylsulfonyl-1-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]piperazin-2-yl]methylamino]cyclobutane-1-carbonitrile | HCID 77148362 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
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| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (10/10) |
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| ORD ID | ord-4d9186bf583846f7a1ce9bf40408eda3 |
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| Source note | Training data from https://doi.org/10.1039/C8SC04228D (10/10) |
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