2-Amino-5-(4-fluorophenyl)thiophene-3-carboxamide → 5-(4-Fluorophenyl)-2-{[6-(1-pyrrolidin-1-ylethyl)pyridin-2-yl]amino}thiophene-3-carboxamide
Reaction equation
[Br:1][c:2]1[n:3][c:4]([CH:8]([CH3:9])[N:10]2[CH2:11][CH2:12][CH2:13][CH2:14]2)[cH:5][cH:6][cH:7]1.[NH2:15][c:16]1[s:17][c:18](-[c:24]2[cH:25][cH:26][c:27]([F:30])[cH:28][cH:29]2)[cH:19][c:20]1[C:21](=[O:22])[NH2:23]>>[c:2]1([NH:15][c:16]2[s:17][c:18](-[c:24]3[cH:25][cH:26][c:27]([F:30])[cH:28][cH:29]3)[cH:19][c:20]2[C:21](=[O:22])[NH2:23])[n:3][c:4]([CH:8]([CH3:9])[N:10]2[CH2:11][CH2:12][CH2:13][CH2:14]2)[cH:5][cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-1024d10823fa44dcb2473d7477bf6f07
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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