Formic Acid → 5-(4-bromo-3-fluorophenyl)-3,4-dihydro-2H-pyrrole

HRID 2348590Notes

Reaction equation

HRID 2348590 reaction equation
[Br:1][c:2]1[c:3]([F:21])[cH:4][c:5]([C:8]([CH2:9][CH2:10][CH2:11][NH:12][C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])=[O:13])[cH:6][cH:7]1.[CH:22]([OH:23])=[O:24]>>[Br:1][c:2]1[c:3]([F:21])[cH:4][c:5]([C:8]2=[N:12][CH2:11][CH2:10][CH2:9]2)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 284Formic AcidHCID 66621053Tert-butyl 4-(4-bromo-3-fluorophenyl)-4-oxobutylcarbamate

Product 1

HCID 666213385-(4-bromo-3-fluorophenyl)-3,4-dihydro-2H-pyrrole

Sources & evidence

ORD record
ord-c979187ee259429fbbfd5b5961920d51
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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