Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | N-Hydroxyphthalimide | HCID 10665 | — |
| Reactant | 1-Bromo-4-(3-bromoprop-1-en-1-yl)benzene | HCID 54519806 | — |
| Solvent | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Product | HCID 54486942 | HCID 54486942 | 86.8% |
Reaction Steps
18.5 g (0.11 mol) of N-hydroxyphthalimide and 31.4 g (0.11 mol) of 1-bromo-3-(4-bromophenyl)-prop-2-ene were added in succession to 350 ml of dry N-methylpyrrolidone, and 12.1 g (0.12 mol) of triethylamine were then added dropwise at room temperature. The reaction mixture was stirred for four days at 20° C. and then poured onto 1.5 l of ice water, and the product was filtered off and washed with water and isopropanol. Yield: 86.8%; m.p.: 161°-162° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05597776 |
|---|
| Source dataset | uspto-grants-1997_01 |
|---|
| ORD ID | ord-7179c8948c4b4b9997e9021025d8aca8 |
|---|
| Source note | uspto-grants-1997_01 |
|---|
