Dichloromethane → HCID 54468234, compound

HRID 234872Notes

Reaction equation

HRID 234872 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]=[CH:9][CH2:10][O:11][N:12]2C(=O)C3=CC=CC=C3C2=O)=[CH:4][CH:3]=1.ClCCl>C(CN)O>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([CH:8]=[CH:9][CH2:10][O:11][NH2:12])=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 6344DichloromethaneHCID 54486942HCID 54486942, compound

Product 1

HCID 54468234HCID 54468234, compoundYield 95.3%

Reagents, catalysts & solvents 1

HCID 700EthanolamineSolvent

Conditions

Temperature
30 °C

Procedure

33.4 g (0.093 mol) of N-[3-(4-bromophenyl)-prop-2-enyloxy]phthalimide were introduced a little at a time in 50 ml of ethanolamine; the temperature increased to 30° C. during this procedure. Stirring was carried out for two hours at 60° C., after which the mixture was allowed to cool and 200 ml of dichloromethane were added. Extraction was effected by shaking with ice water. The organic phase was dried and evaporated down and the residue was crystallized from petroleum ether. Yield: 95.3%; m.p.: 35°-38° C.

Workup

  1. temperatureto cool
  2. extractionExtraction
  3. stirringby shaking with ice water
  4. customThe organic phase was dried
  5. customevaporated down
  6. customthe residue was crystallized from petroleum ether

Sources & evidence

ORD record
ord-2b71b1237e1e4811937a3e7c1dbae9c5
Source dataset
uspto-grants-1997_01
Patent number
US05597776

Reaction notes

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