HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 234878Generated: October 27, 2026
4'-Fluoroacetophenone → HCID 23353093, compound
https://huagongshe.com/reaction/234878
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4'-Fluoroacetophenone | HCID 9828 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | 4-Amino-2-methylpyrimidine-5-carbaldehyde | HCID 12904726 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 23353093 | HCID 23353093 | 50% |
Reaction Steps
15 ml of 40% strength by weight aqueous potassium hydroxide solution were slowly added to a suspension of 30.1 g (0.22 mol) of 4-amino-5-formyl-2-methylpyrimidine and 31.7 g (0.23 mol) of 4-fluoroacetophenone in 395 ml of methanol at 20°-25° C., a homogeneous solution being formed. After the mixture had been stirred for 20 hours at about 20° C., the solid formed was isolated and was recrystallized from ethanol. Yield: 50%; mp.>200° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05597776 |
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| Source dataset | uspto-grants-1997_01 |
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| ORD ID | ord-2ca04429d20f4a3d8462f3ae6d4cb2c2 |
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| Source note | uspto-grants-1997_01 |
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