3-(piperidin-4-yl)-3,4-dihydroquinolin-2(1H)-one → 3-(piperazin-1-yl)-3,4-dihydroquinolin-2(1H)-one

HRID 2348848Notes

Reaction equation

HRID 2348848 reaction equation
[NH:25]1[CH2:26][CH2:27][CH:28]([CH:29]2[CH2:30][c:31]3[c:32]([cH:33][cH:34][cH:35][cH:36]3)[NH:37][C:38]2=[O:39])[CH2:40][CH2:41]1.[O:1]=[C:2]1[NH:3][c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]2[CH2:10][CH:11]1[N:12]1[CH2:13][CH2:14][N:15]([C:18]([O:19][C:20]([CH3:21])([CH3:22])[CH3:23])=[O:24])[CH2:16][CH2:17]1>>[O:1]=[C:2]1[NH:3][c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]2[CH2:10][CH:11]1[N:12]1[CH2:13][CH2:14][NH:15][CH2:16][CH2:17]1

Participants

3

Reactant 2

HCID 183212463-(piperidin-4-yl)-3,4-dihydroquinolin-2(1H)-oneHCID 59732047tert-Butyl 4-(2-oxo-1,2,3,4-tetrahydroquinolin-3-yl)piperazine-1-carboxylate

Product 1

HCID 597319433-(piperazin-1-yl)-3,4-dihydroquinolin-2(1H)-one

Sources & evidence

ORD record
ord-7890b44199c044ceb840df4ca515e30b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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