N-(2-Aminoethyl)methanesulfonamide → N-[2-[[2-amino-5-[[(2,3-difluorophenyl)methyl]thio]thiazolo[4,5-d]pyrimidin-7-yl]amino]ethyl]methanesulfonamide

HRID 2349016Notes

Reaction equation

HRID 2349016 reaction equation
[Cl:1][c:2]1[c:3]2[c:4]([n:5][c:6]([S:8][CH2:9][c:10]3[c:11]([F:17])[c:12]([F:16])[cH:13][cH:14][cH:15]3)[n:7]1)[n:18][c:19]([NH2:21])[s:20]2.[NH2:22][CH2:23][CH2:24][NH:25][S:26](=[O:27])(=[O:28])[CH3:29]>>[c:2]1([NH:22][CH2:23][CH2:24][NH:25][S:26](=[O:27])(=[O:28])[CH3:29])[c:3]2[c:4]([n:5][c:6]([S:8][CH2:9][c:10]3[c:11]([F:17])[c:12]([F:16])[cH:13][cH:14][cH:15]3)[n:7]1)[n:18][c:19]([NH2:21])[s:20]2

Participants

3

Reactant 2

HCID 533845N-(2-Aminoethyl)methanesulfonamideHCID 112216507-Chloro-5-[[(2,3-difluorophenyl)methyl]thio]-thiazolo[4,5-d]pyrimidin-2-amine

Product 1

HCID 22671274N-[2-[[2-amino-5-[[(2,3-difluorophenyl)methyl]thio]thiazolo[4,5-d]pyrimidin-7-yl]amino]ethyl]methanesulfonamide

Sources & evidence

ORD record
ord-5ef297117a2549889096a00834dabbc0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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