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HRID234909

反应详情

EQUATION

反应方程式

HRID 234909 的结构方程式

REACTANTS

反应物

2
结构：O=S(Cl)Cl
HCID24386

Thionyl chloride

Cl2OS

结构：CC[C@@H]1Oc2cc(C(=O)O)ccc2N(C(C)C)C1=O
HCID10515674

未命名化合物

PRODUCTS

生成物

1
结构：CC[C@@H]1Oc2cc(C(=O)Cl)ccc2N(C(C)C)C1=O
HCID22869183

未命名化合物

PROCEDURE

实验过程

A mixture of (S)-2-ethyl-4-(2-propyl)-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-7-carboxylic acid (0.70 g) in thionyl chloride (15 ml) was stirred under reflux for 2 hours. Thionyl chloride was distilled off under reduced pressure to give (S)-2-ethyl-4-(2-propyl)-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-7-carbonyl chloride (0.70 g).

WORKUP

后处理

  1. temperatureunder reflux for 2 hours
  2. distillationThionyl chloride was distilled off under reduced pressure