Thionyl Chloride → HCID 22869180, compound

Participants

Reaction Steps

A mixture of (R)-2-ethyl-4-(2-propyl)-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-7-carboxylic acid (1.60 g) in thionyl chloride (30 ml) was stirred under reflux for 2 hours. Thionyl chloride was distilled off under reduced pressure to give (R)-2-ethyl-4-(2-propyl)-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-7-carbonyl chloride (1.70 g).

Provenance & Evidence