HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-2,4-diethyl-7-methoxycarbonyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine → (S)-2,4-diethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-7-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-2,4-diethyl-7-methoxycarbonyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine | HCID 10825426 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | (S)-2,4-diethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-7-carboxylic acid | HCID 10776998 | 81.7% |
Reaction Steps
A mixture of (S)-2,4-diethyl-7-methoxycarbonyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine (1.90 g) in concentrated hydrochloric acid (40 ml) was stirred under reflux for a day. The concentrated hydrochloric acid was distilled off under reduced pressure to give (S)-2,4-diethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-7-carboxylic acid (1.47 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05597820 |
| Source dataset | uspto-grants-1997_01 |
| ORD ID | ord-dd073c96401043aeb09e1a4fdf2b4797 |
| Source note | uspto-grants-1997_01 |