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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 234929Generated: October 25, 2026

2,4-Dichlorophenylacetonitrile → 6-Benzyloxymethyl-2,4-diamino-5-(2,4-dichlorophenyl)pyrimidine

https://huagongshe.com/reaction/234929

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DichlorophenylacetonitrileHCID 80566—
ReactantEthyl 2-(benzyloxy)acetateHCID 290299—
Reactant2,4-Diamino-5-(2,3-dichlorophenyl)-6-methoxymethylpyrimidineHCID 11522265—
Product6-Benzyloxymethyl-2,4-diamino-5-(2,4-dichlorophenyl)pyrimidineHCID 11523657—

Reaction Steps

This compound was prepared in a manner analogous to the compound of Example 16 from 2,4-dichlorophenylacetonitrile and ethyl benzyloxyacetate, 3.77 gms, mp. 171°-172° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05597827
Source datasetuspto-grants-1997_01
ORD IDord-b340b204a63f47dcbcbe6ce517894b9c
Source noteuspto-grants-1997_01