Acetate → Prednisolone, 1,2-dihydro-9,11-dedihydro-11-desoxy-, 21-acetate(ester)
Reaction equation
[CH2:37]([Cl:38])[Cl:39].[CH3:27][C:28]([O-:29])=[O:30].[CH3:33][C:34](=[O:35])[CH3:36].[Cl:1][CH2:2][C:3]([C:4]1([OH:24])[CH2:5][CH2:6][CH:7]2[CH:8]3[CH2:9][CH2:10][C:11]4=[CH:12][C:13](=[O:23])[CH2:14][CH2:15][C:16]4([CH3:17])[C:18]3=[CH:19][CH2:20][C:21]12[CH3:22])=[O:25].[I-:32].[K+:26].[K+:31]>>[CH2:2]([C:3]([C:4]1([OH:24])[CH2:5][CH2:6][CH:7]2[CH:8]3[CH2:9][CH2:10][C:11]4=[CH:12][C:13](=[O:23])[CH2:14][CH2:15][C:16]4([CH3:17])[C:18]3=[CH:19][CH2:20][C:21]12[CH3:22])=[O:25])[O:30][C:28]([CH3:27])=[O:29]Participants
7
Sources & evidence
- ORD record
- ord-46d42681ef5246c68929f1d2026cff7a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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