2,4-Dichlorophenylacetonitrile → HCID 23353546, compound

HRID 234941Notes

Reaction equation

HRID 234941 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]([NH2:8])[C:5]([C:9]2[CH:14]=[CH:13][CH:12]=[C:11](Cl)[C:10]=2[Cl:16])=[C:4]([CH:17]([O:21][CH2:22][CH3:23])[O:18][CH2:19][CH3:20])[N:3]=1.[Cl:24]C1C=C(Cl)C=CC=1CC#N>>[NH2:1][C:2]1[N:7]=[C:6]([NH2:8])[C:5]([C:9]2[CH:14]=[CH:13][C:12]([Cl:24])=[CH:11][C:10]=2[Cl:16])=[C:4]([CH:17]([O:21][CH2:22][CH3:23])[O:18][CH2:19][CH3:20])[N:3]=1

Participants

3

Reactant 2

HCID 805662,4-DichlorophenylacetonitrileHCID 23294078HCID 23294078, compound

Product 1

HCID 23353546HCID 23353546, compound

Procedure

This compound was prepared in a manner analogous to 2,4-diamino-5-(2,3-dichlorophenyl)-6-(diethoxymethyl)pyrimidine (Example 18.1) from 2,4-dichlorophenylacetonitrile, mp. 225° C.

Sources & evidence

ORD record
ord-25e97e0744e4428ab926040ca2c39cd9
Source dataset
uspto-grants-1997_01
Patent number
US05597827

Reaction notes

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