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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2349501Generated: October 31, 2026

Methanol → N-(5-(2,2-difluoro-6-methylbenzo[d][1,3]dioxol-5-yl)pyridin-2-yl)-2,6-difluorobenzamide

https://huagongshe.com/reaction/2349501

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantSodium ionHCID 923—
ReactantHydroxideHCID 961—
ReactantDichloromethaneHCID 6344—
ReactantTetrahydrofuranHCID 8028—
ReactantDiisopropylethylamineHCID 81531—
Reactant2,6-Difluorobenzoyl chlorideHCID 87438—
Reactant5-(2,2-Difluoro-6-methylbenzo[d][1,3]dioxol-5-yl)pyridin-2-amineHCID 58486652—
ProductN-(5-(2,2-difluoro-6-methylbenzo[d][1,3]dioxol-5-yl)pyridin-2-yl)-2,6-difluorobenzamideHCID 58486781—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (10/10)
ORD IDord-1a3fecc7150a494da82d976654379d9d
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (10/10)