2-Piperazin-1-yl-thiazole-5-carbonitrile → 2-{4-[5-Methanesulfonyl-2-(2,2,2-trifluoro-ethoxy)-benzoyl]-piperazin-1-yl}-thiazole-5-carbonitrile
Reaction equation
[CH3:1][S:2](=[O:3])(=[O:4])[c:5]1[cH:6][cH:7][c:8]([O:14][CH2:15][C:16]([F:17])([F:18])[F:19])[c:9]([C:10](=[O:11])[OH:12])[cH:13]1.[N:20]1([c:26]2[s:27][c:28]([C:31]#[N:32])[cH:29][n:30]2)[CH2:21][CH2:22][NH:23][CH2:24][CH2:25]1>>[CH3:1][S:2](=[O:3])(=[O:4])[c:5]1[cH:6][cH:7][c:8]([O:14][CH2:15][C:16]([F:17])([F:18])[F:19])[c:9]([C:10](=[O:12])[N:23]2[CH2:22][CH2:21][N:20]([c:26]3[s:27][c:28]([C:31]#[N:32])[cH:29][n:30]3)[CH2:25][CH2:24]2)[cH:13]1Participants
3
Sources & evidence
- ORD record
- ord-d35cc177c2d149c5a15b90cb30d916e8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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