2-{2-[4-(2-Bromo-ethyl)-phenyl]-ethyl}-isoindole-1,3-dione → 2-[2-(4-{2-[4-({3-[hydroxy(diphenyl)methyl]-1H-1,2,4-triazol-1-yl}methyl)piperidin-1-yl]ethyl}phenyl)ethyl]-1H-isoindole-1,3(2H)-dione

HRID 2349775Notes

Reaction equation

HRID 2349775 reaction equation
[Br:27][CH2:28][CH2:29][c:30]1[cH:31][cH:32][c:33]([CH2:36][CH2:37][N:38]2[C:39](=[O:48])[c:40]3[cH:41][cH:42][cH:43][cH:44][c:45]3[C:46]2=[O:47])[cH:34][cH:35]1.[c:1]1([C:7]([OH:8])([c:9]2[n:10][n:11]([CH2:14][CH:15]3[CH2:16][CH2:17][NH:18][CH2:19][CH2:20]3)[cH:12][n:13]2)[c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([C:7]([OH:8])([c:9]2[n:10][n:11]([CH2:14][CH:15]3[CH2:16][CH2:17][N:18]([CH2:28][CH2:29][c:30]4[cH:31][cH:32][c:33]([CH2:36][CH2:37][N:38]5[C:39](=[O:48])[c:40]6[cH:41][cH:42][cH:43][cH:44][c:45]6[C:46]5=[O:47])[cH:34][cH:35]4)[CH2:19][CH2:20]3)[cH:12][n:13]2)[c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

3

Reactant 2

HCID 591459472-{2-[4-(2-Bromo-ethyl)-phenyl]-ethyl}-isoindole-1,3-dioneHCID 59145965Diphenyl[1-(piperidin-4-ylmethyl)-1H-1,2,4-triazol-3-yl]methanol

Product 1

HCID 591459442-[2-(4-{2-[4-({3-[hydroxy(diphenyl)methyl]-1H-1,2,4-triazol-1-yl}methyl)piperidin-1-yl]ethyl}phenyl)ethyl]-1H-isoindole-1,3(2H)-dione

Sources & evidence

ORD record
ord-9ae59ee940b2466e847c52ceedba2094
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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