HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → 6-tert-Butyl-7-mercapto-1,4-dihydro-quinoxaline-2,3-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | 6-Tert-butyl-7-thiocyanato-1,4-dihydro-quinoxaline-2,3-dione | HCID 22572876 | — |
| Reactant | Sodium hydrogen sulphide | HCID 86586439 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Solvent | Water | HCID 962 | — |
| Product | 6-tert-Butyl-7-mercapto-1,4-dihydro-quinoxaline-2,3-dione | HCID 22572795 | — |
Reaction Steps
The title compound was prepared according to General Method 14b using 6-tert-butyl-7-thiocyanato-1,4-dihydro-quinoxaline-2,3-dione (prepared in Example CCC; 1.5 g, 9.1 mmol), sodium hydrogen sulfide (0.51 g, 27 mmol), sodium borohydride (2.1 g, 55 mmol). MeOH (30 mL), H2O (3 mL), and glacial AcOH (5 mL). The crude product was used without purification. MS(APCI): 251 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06852711B2 |
| Source dataset | uspto-grants-2005_02 |
| ORD ID | ord-c1fb75527546481183c8b2513d97bd04 |
| Source note | uspto-grants-2005_02 |