3-Aminophenol → N4-(4-chloro-2,5-dimethoxyphenyl)-5-fluoro-N2-(3-hydroxyphenyl)-2,4-pyrimidinediamine

HRID 2349971Notes

Reaction equation

HRID 2349971 reaction equation
[Cl:9][c:10]1[n:11][cH:12][c:13]([F:28])[c:14]([NH:16][c:17]2[c:18]([O:26][CH3:27])[cH:19][c:20]([Cl:25])[c:21]([O:23][CH3:24])[cH:22]2)[n:15]1.[OH:1][c:2]1[cH:3][c:4]([NH2:5])[cH:6][cH:7][cH:8]1>>[OH:1][c:2]1[cH:3][c:4]([NH:5][c:10]2[n:11][cH:12][c:13]([F:28])[c:14]([NH:16][c:17]3[c:18]([O:26][CH3:27])[cH:19][c:20]([Cl:25])[c:21]([O:23][CH3:24])[cH:22]3)[n:15]2)[cH:6][cH:7][cH:8]1

Participants

3

Reactant 2

HCID 115683-AminophenolHCID 220606222-chloro-N4-(2,5-dimethoxy-4-chlorophenyl)-5-fluoro-4-pyrimidineamine

Product 1

HCID 66759583N4-(4-chloro-2,5-dimethoxyphenyl)-5-fluoro-N2-(3-hydroxyphenyl)-2,4-pyrimidinediamine

Sources & evidence

ORD record
ord-29ab0e5e45d44e46b08f3a4d5f132d6d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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