2,4-Diamino-5-(2,3-dichlorophenyl)-6-methylpyrimidine → 2,4-Diamino-5-(2,3-dichloro-4-nitrophenyl)-6-methylpyrimidine

HRID 235015Notes

Reaction equation

HRID 235015 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]([NH2:8])[C:5]([C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([Cl:15])[C:10]=2[Cl:16])=[C:4]([CH3:17])[N:3]=1.NC1N=C(N)C(C2C=CC([N+:32]([O-:34])=[O:33])=CC=2C2C=CC=C(Cl)C=2Cl)=CN=1.NC1N=C(N)C(C2C=C([N+]([O-])=O)C=C(Cl)C=2Cl)=C(C)N=1>>[NH2:1][C:2]1[N:7]=[C:6]([NH2:8])[C:5]([C:9]2[CH:14]=[CH:13][C:12]([N+:32]([O-:34])=[O:33])=[C:11]([Cl:15])[C:10]=2[Cl:16])=[C:4]([CH3:17])[N:3]=1

Participants

4

Reactant 3

HCID 116734192,4-Diamino-5-(2,3-dichlorophenyl)-6-methylpyrimidineHCID 197050892,4-Diamino-5-(2,3-dichlorophenyl-4-nitrophenyl)pyrimidineHCID 197051082,4-Diamino-5(2,3-dichloro-5-nitrophenyl)-6-methylpyrimidine

Product 1

HCID 197050312,4-Diamino-5-(2,3-dichloro-4-nitrophenyl)-6-methylpyrimidine

Procedure

This compound was made from the compound of Example 15 in an analogous manner to the compound of Example 39, mp. 265° C. Also obtained from this reaction was 2,4-diamino-5(2,3-dichloro-5-nitrophenyl)-6-methyl pyrimidine.

Workup

  1. customAlso obtained from this reaction

Sources & evidence

ORD record
ord-fe321eeae79b4bcdbe2282678e7450ba
Source dataset
uspto-grants-1997_01
Patent number
US05597828

Reaction notes

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