Dichloromethane → Tert-butyl {trans-4-[2-fluoro-2-(2-fluorophenyl)ethoxy]-cyclohexyl}carbamate
Reaction equation
[CH2:26]([S:27]([F:28])([F:29])([CH2:30][CH3:31])([F:32])[NH2:33])[CH3:34].[Cl:35][CH2:36][Cl:37].[F:1][c:2]1[c:3]([CH:8]([CH2:9][O:10][CH:11]2[CH2:12][CH2:13][CH:14]([NH:17][C:18]([O:19][C:20]([CH3:21])([CH3:22])[CH3:23])=[O:24])[CH2:15][CH2:16]2)[OH:25])[cH:4][cH:5][cH:6][cH:7]1>>[F:1][c:2]1[c:3]([CH:8]([CH2:9][O:10][CH:11]2[CH2:12][CH2:13][CH:14]([NH:17][C:18]([O:19][C:20]([CH3:21])([CH3:22])[CH3:23])=[O:24])[CH2:15][CH2:16]2)[F:32])[cH:4][cH:5][cH:6][cH:7]1Participants
4
Sources & evidence
- ORD record
- ord-773e7736d0554d1fbc234b568b349f33
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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