Methyl 3-[4-(4-cyanophenyl)phenyl]-2-[[3-[4-[(3,4-dichlorophenyl)methoxy]phenyl]-2,3,6,7,8,9-hexahydro-[1,4]dioxino[2,3-g]isoquinoline-8-carbonyl]amino]propanoate → methyl 3-[4-(4-cyanophenyl)phenyl]-2-[[3-[4-[(3,4-dichlorophenyl)methoxy]phenyl]-7-[[2-[(2-methylpropan-2-yl)oxycarbonylamino]-1,3-benzothiazol-6-yl]sulfonyl]-3,6,8,9-tetrahydro-2H-[1,4]dioxino[2,3-g]isoquinoline-8-carbonyl]amino]propanoate
Reaction equation
[C:54]([CH3:55])([CH3:56])([CH3:57])[O:58][C:59]([NH:60][c:61]1[s:62][c:63]2[c:64]([n:65]1)[cH:66][cH:67][c:68]([S:70](=[O:71])(=[O:72])[Cl:73])[cH:69]2)=[O:74].[CH3:1][O:2][C:3]([CH:4]([CH2:5][c:6]1[cH:7][cH:8][c:9](-[c:12]2[cH:13][cH:14][c:15]([C:18]#[N:19])[cH:16][cH:17]2)[cH:10][cH:11]1)[NH:20][C:21](=[O:22])[CH:23]1[NH:24][CH2:25][c:26]2[cH:27][c:28]3[c:29]([cH:30][c:31]2[CH2:32]1)[O:33][CH2:34][CH:35]([c:37]1[cH:38][cH:39][c:40]([O:43][CH2:44][c:45]2[cH:46][c:47]([Cl:52])[c:48]([Cl:51])[cH:49][cH:50]2)[cH:41][cH:42]1)[O:36]3)=[O:53]>>[CH3:1][O:2][C:3]([CH:4]([CH2:5][c:6]1[cH:7][cH:8][c:9](-[c:12]2[cH:13][cH:14][c:15]([C:18]#[N:19])[cH:16][cH:17]2)[cH:10][cH:11]1)[NH:20][C:21](=[O:22])[CH:23]1[N:24]([S:70]([c:68]2[cH:67][cH:66][c:64]3[c:63]([s:62][c:61]([NH:60][C:59]([O:58][C:54]([CH3:55])([CH3:56])[CH3:57])=[O:74])[n:65]3)[cH:69]2)(=[O:71])=[O:72])[CH2:25][c:26]2[cH:27][c:28]3[c:29]([cH:30][c:31]2[CH2:32]1)[O:33][CH2:34][CH:35]([c:37]1[cH:38][cH:39][c:40]([O:43][CH2:44][c:45]2[cH:46][c:47]([Cl:52])[c:48]([Cl:51])[cH:49][cH:50]2)[cH:41][cH:42]1)[O:36]3)=[O:53]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-196e9d1b3ab2453695f31c139be5bb9e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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