Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2350331Generated: October 28, 2026

Hydrochloric Acid → (RS)-2-{1-(bis(4-chlorophenyl)methyl]azetidin-3-yl}-2-(3,5-difluorophenyl)-N-methylacetamide

https://huagongshe.com/reaction/2350331

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantWaterHCID 962—
ReactantMethylamineHCID 6329—
ReactantDichloromethaneHCID 6344—
ReactantTetrahydrofuranHCID 8028—
ReactantTriethylamineHCID 8471—
Reactant1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 15908—
Reactant(RS)-2-{1-[Bis(4-chlorophenyl)methyl]-azetidin-3-yl}-2-(3,5-difluorophenyl)-N-propylacetamideHCID 22506657—
Reactant2-[1-[Bis(4-chlorophenyl)methyl]azetidin-3-yl]-2-(3,5-difluorophenyl)acetic acidHCID 22506702—
ReactantHCID 178418300HCID 178418300—
Product(RS)-2-{1-(bis(4-chlorophenyl)methyl]azetidin-3-yl}-2-(3,5-difluorophenyl)-N-methylacetamideHCID 22506786—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (10/10)
ORD IDord-8c676ee1d1034aefbec14662d33c2d53
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (10/10)