HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 5-[2-tert-butyl-4-(hydroxymethyl)-5-methyl-phenyl]sulfanyl-2-[2-(2-furyl)ethyl]-4-hydroxy-2-isopropyl-3H-pyran-6-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | S-[2-Tert-butyl-4-(hydroxymethyl)-5-methylphenyl] 4-methylbenzenesulfonothioate | HCID 10499026 | — |
| Reactant | 6-(2-Furan-2-yl-ethyl)-4-hydroxy-6-isopropyl-5,6-dihydro-pyran-2-one | HCID 54705160 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 5-[2-tert-butyl-4-(hydroxymethyl)-5-methyl-phenyl]sulfanyl-2-[2-(2-furyl)ethyl]-4-hydroxy-2-isopropyl-3H-pyran-6-one | HCID 54677051 | — |
Reaction Steps
The title compound was prepared as described in General Method 16a using 6-(2-furan-2-yl-ethyl)-4-hydroxy-6-isopropyl-5,6-dihydro-pyran-2-one (Example E-17; 1 mmol), toluene-4-thiosulfonic acid S-(2-tert-butyl-4-hydroxymethyl-5-methyl-phenyl)ester (Example BB-2; 1.1 mmol), potassium carbonate (4 mmol) in DMF (5 mL) mp 64-110° C. MS (APCI): 457 (M−H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06852711B2 |
| Source dataset | uspto-grants-2005_02 |
| ORD ID | ord-33c8e64f93bf448d8862db834a1d0ff1 |
| Source note | uspto-grants-2005_02 |