Methanesulfonyl chloride → HCID 19705059, compound

HRID 235041Notes

Reaction equation

HRID 235041 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]([NH2:8])[C:5]([C:9]2[CH:14]=[C:13]([NH2:15])[CH:12]=[CH:11][C:10]=2[Cl:16])=[C:4]([CH3:17])[N:3]=1.[CH3:18][S:19](Cl)(=[O:21])=[O:20]>N1C=CC=CC=1>[NH2:1][C:2]1[N:7]=[C:6]([NH2:8])[C:5]([C:9]2[CH:14]=[C:13]([NH:15][S:19]([CH3:18])(=[O:21])=[O:20])[CH:12]=[CH:11][C:10]=2[Cl:16])=[C:4]([CH3:17])[N:3]=1

Participants

4

Reactant 2

HCID 31297Methanesulfonyl chlorideHCID 19705127HCID 19705127, compound

Product 1

HCID 19705059HCID 19705059, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

This compound was prepared from 2,4-diamino-5-(2-chloro-5-aminophenyl) -6-methylpyrimidine from Example 54 by reaction with methanesulphonylchloride in pyridine, mp. 234°≅240° C.

Workup

  1. custom≅240° C.

Sources & evidence

ORD record
ord-59f09693c0964be695a42603a79ac799
Source dataset
uspto-grants-1997_01
Patent number
US05597828

Reaction notes

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