3,5-dichloro-1-(1-cyclobutylpropyl)-2(1H)-pyrazinone → 5-chloro-1-(1-cyclobutylpropyl)-3-(7-methoxy-2,3-dihydro-4H-1,4-benzoxazin-4-yl)-2(1H)-pyrazinone

HRID 2350517Notes

Reaction equation

HRID 2350517 reaction equation
[CH3:17][O:18][c:19]1[cH:20][c:21]2[c:22]([cH:27][cH:28]1)[NH:23][CH2:24][CH2:25][O:26]2.[Cl:1][c:2]1[c:3](=[O:16])[n:4]([CH:9]([CH2:10][CH3:11])[CH:12]2[CH2:13][CH2:14][CH2:15]2)[cH:5][c:6]([Cl:8])[n:7]1>>[c:2]1([N:23]2[c:22]3[c:21]([cH:20][c:19]([O:18][CH3:17])[cH:28][cH:27]3)[O:26][CH2:25][CH2:24]2)[c:3](=[O:16])[n:4]([CH:9]([CH2:10][CH3:11])[CH:12]2[CH2:13][CH2:14][CH2:15]2)[cH:5][c:6]([Cl:8])[n:7]1

Participants

3

Reactant 2

HCID 184527943,5-dichloro-1-(1-cyclobutylpropyl)-2(1H)-pyrazinoneHCID 198950027-methoxy-3,4-dihydro-2H-1,4-benzoxazine

Product 1

HCID 102003765-chloro-1-(1-cyclobutylpropyl)-3-(7-methoxy-2,3-dihydro-4H-1,4-benzoxazin-4-yl)-2(1H)-pyrazinone

Sources & evidence

ORD record
ord-00bbeeca3140416bab96b682df25e044
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

Loading…