HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → HCID 2805874, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | Methyl Thioglycolate | HCID 16907 | — |
| Reactant | 1,3-Benzenedicarbonitrile, 2-chloro- | HCID 206674 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 2805874 | HCID 2805874 | 65% |
Reaction Steps
2-chloro-1,3-dicyanobenzene (972 mg, 6.0 mmol) was treated with 1 eq of methyl thioglycolate and 1 eq sodium carbonate in methanol as described in Example 41A to give the title compound in 65% yield. 1H NMR (300 MHz, D6-DMSO d 3.83 (s, 3H), 7.38 (bs, 2H), 7.62 (t, J=8 Hz, 1H), 8.10 (d, J=8 Hz, 1H), 8.50 (d, J=8 Hz, 1H). MS (DCI/NH3) m/e 250 (M+NH4)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05597823 |
| Source dataset | uspto-grants-1997_01 |
| ORD ID | ord-6cafb57aa6474fc5ac3a00dc979970e5 |
| Source note | uspto-grants-1997_01 |